improved resolution in serum protein immunofixation electrophoresis

Attenuated Induction of the Unfolded Protein Response in Grownup Human Major Astrocytes in Response to Recurrent Low Glucose

Goals/speculation: Recurrent hypoglycaemia (RH) is a serious side-effect of intensive insulin remedy for individuals with diabetes. Modifications in hypoglycaemia sensing by the mind contribute to the event of impaired counterregulatory responses to and consciousness of hypoglycaemia. Little is understood in regards to the intrinsic adjustments in human astrocytes in response to acute and recurrent low glucose (RLG) publicity.

Strategies: Human main astrocytes (HPA) have been uncovered to zero, one, three or 4 bouts of low glucose (0.1 mmol/l) for 3 hours per day for 4 days to imitate RH. On the fourth day, DNA and RNA have been collected. Differential gene expression and ontology analyses have been carried out utilizing DESeq2 and GOseq, respectively. DNA methylation was assessed utilizing the Infinium MethylationEPIC BeadChip platform.

Outcomes: 24 differentially expressed genes (DEGs) have been detected (after correction for a number of comparisons). One bout of low glucose publicity had the most important impact on gene expression. Pathway analyses revealed that endoplasmic-reticulum (ER) stress-related genes comparable to HSPA5XBP1, and MANF, concerned within the unfolded protein response (UPR), have been all considerably elevated following low glucose (LG) publicity, which was diminished following RLG. There was little correlation between differentially methylated positions and adjustments in gene expression but the variety of bouts of LG publicity produced distinct methylation signatures.

Conclusions/interpretation: These information recommend that publicity of human astrocytes to transient LG triggers activation of genes concerned within the UPR linked to endoplasmic reticulum (ER) stress. Following RLG, the activation of UPR associated genes was diminished, suggesting attenuated ER stress. This can be a consequence of a profitable metabolic adaptation, as beforehand reported, that higher preserves intracellular vitality ranges and a decreased necessity for the UPR.

Click on Chemistry for Imaging in-situ Protein Palmitoylation in the course of the Asexual Phases of Plasmodium falciparum

Palmitoylation refers back to the modification of the cysteine thiols in proteins by fatty acids, mostly palmitic acid, by way of ‘thioester bond’ formation. In vivo, palmitoylation of proteins is catalyzed by palmitoyl acyltransferases (PATs or DHHC-PATs). Palmitoylation has not too long ago emerged as an important post-translational modification in malarial parasites. The expression and exercise of palmitoyl transferases range throughout completely different developmental phases of the malarial parasite’s life cycle. The abundance of palmitoylated proteins at a given stage is a measure of total PAT exercise. The PAT exercise can even change in response to exterior alerts or inhibitors.

Right here, we describe a protocol to ‘picture’ palmitoyl-transferase exercise in the course of the asexual phases utilizing Click on Chemistry and fluorescence microscopy. This technique relies on metabolic labeling of a clickable analog of palmitic acid by parasitic cells, adopted by CuAAC (Copper-catalyzed Alkyne-Azide Cycloaddition response) Click on Chemistry to render palmitoylated proteins fluorescent. Fluorescence permits the quantitation of intracellular palmitoylation in parasite cells throughout numerous improvement phases. Utilizing this technique, we noticed that intracellular palmitoylation will increase because the parasite transitions from ring to schizont phases and seems to be most plentiful in the course of the schizont phases in Plasmodium falciparum.

proteomicssurf
proteomicssurf

Human Nuclear pore complex protein Nup153 (NUP153)

1-CSB-EP016190HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Nuclear pore complex protein Nup153(NUP153),partial expressed in E.coli

Recombinant human Nuclear pore complex protein Nup133

P2220 100ug Ask for price
Description: Recombinant protein for human Nuclear pore complex protein Nup133

Panspecific Nuclear Pore Complex Marker

MO22107 500 ul
EUR 412.8

Human Nuclear pore complex protein Nup85, NUP85 ELISA KIT

ELI-36779h 96 Tests
EUR 988.8

Human Nuclear pore complex protein Nup88, NUP88 ELISA KIT

ELI-36780h 96 Tests
EUR 988.8

Human Nuclear pore complex protein Nup93, NUP93 ELISA KIT

ELI-36781h 96 Tests
EUR 988.8

Mouse Nuclear pore complex protein Nup93, Nup93 ELISA KIT

ELI-44561m 96 Tests
EUR 1038

Mouse Nuclear pore complex protein Nup88, Nup88 ELISA KIT

ELI-35536m 96 Tests
EUR 1038

Human Nuclear pore complex protein Nup50, NUP50 ELISA KIT

ELI-22432h 96 Tests
EUR 988.8

Mouse Nuclear pore complex protein Nup85, Nup85 ELISA KIT

ELI-23492m 96 Tests
EUR 1038

Mouse Nuclear pore complex protein Nup54, Nup54 ELISA KIT

ELI-21319m 96 Tests
EUR 1038

Mouse Nuclear pore complex protein Nup50, Nup50 ELISA KIT

ELI-15055m 96 Tests
EUR 1038

Bovine Nuclear pore complex protein Nup93, NUP93 ELISA KIT

ELI-44229b 96 Tests
EUR 1113.6

Bovine Nuclear pore complex protein Nup85, NUP85 ELISA KIT

ELI-23491b 96 Tests
EUR 1113.6

Human Nuclear pore complex protein Nup107, NUP107 ELISA KIT

ELI-36840h 96 Tests
EUR 988.8

Mouse Nuclear pore complex protein Nup107, Nup107 ELISA KIT

ELI-38239m 96 Tests
EUR 1038

Human Nuclear pore complex protein Nup160, NUP160 ELISA KIT

ELI-38240h 96 Tests
EUR 988.8

Human Nuclear pore complex protein Nup205, NUP205 ELISA KIT

ELI-38242h 96 Tests
EUR 988.8

Human Nuclear pore complex protein Nup133, NUP133 ELISA KIT

ELI-46087h 96 Tests
EUR 988.8

Mouse Nuclear pore complex protein Nup155, Nup155 ELISA KIT

ELI-44221m 96 Tests
EUR 1038

Human Nuclear pore complex protein Nup214, NUP214 ELISA KIT

ELI-44222h 96 Tests
EUR 988.8

Mouse Nuclear pore complex protein Nup133, Nup133 ELISA KIT

ELI-44499m 96 Tests
EUR 1038

Human Nuclear pore complex protein Nup153, NUP153 ELISA KIT

ELI-44867h 96 Tests
EUR 988.8

Mouse Nuclear pore complex protein Nup160, Nup160 ELISA KIT

ELI-21357m 96 Tests
EUR 1038

Mouse Nuclear pore complex protein Nup214, Nup214 ELISA KIT

ELI-21358m 96 Tests
EUR 1038

Human Nuclear pore complex protein Nup155, NUP155 ELISA KIT

ELI-15040h 96 Tests
EUR 988.8

ELISA kit for Rat Nuclear pore complex protein Nup153 (NUP153)

KTE100879-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Rat Nuclear pore complex protein Nup153 (NUP153) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear pore complex protein Nup153 (NUP153)

KTE100879-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Rat Nuclear pore complex protein Nup153 (NUP153) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear pore complex protein Nup153 (NUP153)

KTE100879-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Rat Nuclear pore complex protein Nup153 (NUP153) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human Nuclear pore complex protein Nup98- Nup96, NUP98 ELISA KIT

ELI-13775h 96 Tests
EUR 988.8

Nuclear pore membrane glycoprotein 210 Polyclonal Conjugated Antibody

C42276 100ul
EUR 476.4

Human Nuclear pore complex- interacting protein, NPIP ELISA KIT

ELI-16689h 96 Tests
EUR 988.8

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-10ug

QP6439-ec-10ug 10ug
EUR 240

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-1mg

QP6439-ec-1mg 1mg
EUR 1958.4

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-50ug

QP6439-ec-50ug 50ug
EUR 315.6

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-100ug

QP6439-ec-100ug 100ug
EUR 489.6

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-200ug

QP6439-ec-200ug 200ug
EUR 760.8

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-500ug

QP6439-ec-500ug 500ug
EUR 1272

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

abx237677-100ug 100 ug
EUR 610.8

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

abx025879-400ul 400 ul
EUR 627.6

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

abx025879-80l 80 µl
EUR 343.2

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

20-abx126518
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

20-abx123660
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Nuclear Matrix Protein p84 Conjugated Antibody

C49738 100ul
EUR 476.4

Human Elongator Complex Protein 4 (ELP4) AssayLite Antibody (FITC Conjugate)

32270-05141 150 ug
EUR 513.6

Anti-Nuclear pore Complex antibody

STJ120173 100 µl
EUR 562.8

Nuclease P1 Antibody, FITC conjugated

1-CSB-PA328459LC01PEU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Nuclease P1. Recognizes Nuclease P1 from Penicillium citrinum. This antibody is FITC conjugated. Tested in the following application: ELISA

Nuclear pore membrane glycoprotein 210 Antibody (FITC)

20-abx107147
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Pyruvate Dehydrogenase Complex (PDH Complex) AssayLite Antibody (FITC Conjugate)

30022-05141 150 ug
EUR 513.6

Human SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) ELISA Kit

abx383083-96tests 96 tests
EUR 1093.2

Human Nuclear Cap-Binding Protein Subunit 2 (NCBP2) AssayLite Antibody (FITC Conjugate)

30189-05141 150 ug
EUR 513.6

Nuclease P1 Polyclonal Antibody, FITC Conjugated

A64320
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Pyruvate Dehydrogenase Complex (PDH Complex) AssayLite Antibody (FITC, RPE, APC, PerCP Conjugate)

30022-05181 1 x 75 ug, 3 x 30 ug
EUR 702

Nuclear Receptor NR4A1 (Ab-351) Conjugated Antibody

C33181 100ul
EUR 476.4

Histone Complex (H1, H2A, H2B, H3, H4) AssayLite Antibody (FITC Conjugate)

30200-05141 150 ug
EUR 513.6

Histone Core Complex (H2A, H2B, H3, H4) AssayLite Antibody (FITC Conjugate)

30198-05141 150 ug
EUR 513.6

Human Nuclear Transport Factor 2 (NTF-2) AssayLite Antibody (FITC Conjugate)

32033-05141 150 ug
EUR 513.6

Small Nuclear Ribonucleoprotein (snRNP, RNP-Sm) AssayLite Antibody (FITC Conjugate)

31359-05141 150 ug
EUR 513.6

Nuclear receptor ROR-gamma Polyclonal Conjugated Antibody

C42312 100ul
EUR 476.4

Nuclear Pore Associated Protein 1 (NPAP1) Antibody

20-abx339916
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Nuclear Pore Associated Protein 1 (NPAP1) Antibody

20-abx339917
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Actin-related protein 2/3 complex subunit 3 Polyclonal Conjugated Antibody

C42389 100ul
EUR 476.4

Small Nuclear Ribonucleoprotein Sm D (Sm D1, D2, D3) AssayLite Antibody (FITC Conjugate)

31360-05141 150 ug
EUR 513.6

Proteasome activator complex subunit 3 Polyclonal Conjugated Antibody

C42571 100ul
EUR 476.4

Small nuclear ribonucleoprotein G Polyclonal Conjugated Antibody

C42264 100ul
EUR 476.4

Nucleoprotein Polyclonal Antibody, FITC Conjugated

A55012 100 µg
EUR 684.66

Nucleoprotein Polyclonal Antibody, FITC Conjugated

A55509
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Nucleoprotein Polyclonal Antibody, FITC Conjugated

A57826
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

AP-2 complex subunit sigma Polyclonal Conjugated Antibody

C42366 100ul
EUR 476.4

Small Nuclear Ribonucleoprotein A (U1 snRNP A, RNP-A) AssayLite Antibody (FITC Conjugate)

31362-05141 150 ug
EUR 513.6

Small Nuclear Ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) AssayLite Antibody (FITC Conjugate)

31363-05141 150 ug
EUR 513.6

U1 small nuclear ribonucleoprotein A Polyclonal Conjugated Antibody

C42190 100ul
EUR 476.4

Small nuclear ribonucleoprotein Sm D2 Polyclonal Conjugated Antibody

C42367 100ul
EUR 476.4

AP-1 complex subunit sigma-3 Polyclonal Conjugated Antibody

C42067 100ul
EUR 476.4

Heterogeneous nuclear ribonucleoprotein A1 Polyclonal Conjugated Antibody

C42208 100ul
EUR 476.4

Heterogeneous nuclear ribonucleoprotein D0 Polyclonal Conjugated Antibody

C42362 100ul
EUR 476.4

Heterogeneous nuclear ribonucleoprotein Q Polyclonal Conjugated Antibody

C42390 100ul
EUR 476.4

Heterogeneous nuclear ribonucleoprotein H Polyclonal Conjugated Antibody

C42411 100ul
EUR 476.4

COP9 signalosome complex subunit 7a Polyclonal Conjugated Antibody

C42685 100ul
EUR 476.4

Small Nuclear RNA Activating Complex Polypeptide 5 (SNAPC5) Antibody

abx238059-100ug 100 ug
EUR 661.2

Small Nuclear RNA Activating Complex Polypeptide 5 (SNAPC5) Antibody

20-abx218687
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Small Nuclear RNA Activating Complex Polypeptide 5 (SNAPC5) Antibody

20-abx325174
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Human Elongator Complex Protein 4 (ELP4) Antibody (Biotin Conjugate)

32270-05121 150 ug
EUR 442.8

Guanine nucleotide-binding protein subunit beta-like protein Antibody, FITC conjugated

1-CSB-PA659907LC01GGV
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Guanine nucleotide-binding protein subunit beta-like protein. Recognizes Guanine nucleotide-binding protein subunit beta-like protein from Glycine max. This antibody is FITC conjugated. Tested in the following application: ELISA

Anaphase-promoting complex subunit 5 Polyclonal Conjugated Antibody

C42423 100ul
EUR 476.4

Nuclear Pore-Associated Protein 60 kDa-Like (Npap60) Antibody

abx430652-200ul 200 ul
EUR 460.8

Nuclear factor NF-kappa-B p105 subunit 1 Polyclonal Conjugated Antibody

C42522 100ul
EUR 476.4

Human Complexin-1 (CPX I) AssayLite Antibody (FITC Conjugate)

30025-05141 150 ug
EUR 513.6

Small Nuclear Ribonucleoprotein (snRNP, RNP-Sm) AssayLite Antibody (FITC, RPE, APC, PerCP Conjugate)

31359-05181 1 x 75 ug, 3 x 30 ug
EUR 702

Nuclear pore membrane glycoprotein 210 Antibody

20-abx110055
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Elongator Complex Protein 4 (ELP4) AssayLite Antibody (RPE Conjugate)

32270-05151 150 ug
EUR 513.6

Human Elongator Complex Protein 4 (ELP4) AssayLite Antibody (APC Conjugate)

32270-05161 150 ug
EUR 513.6

Human Elongator Complex Protein 4 (ELP4) AssayLite Antibody (PerCP Conjugate)

32270-05171 150 ug
EUR 565.2

Pyruvate Dehydrogenase Complex (PDH Complex) Antibody (Biotin Conjugate)

30022-05121 150 ug
EUR 442.8

Small Nuclear Ribonucleoprotein A (U1 snRNP A, RNP-A) AssayLite Antibody (FITC, RPE, APC, PerCP Conjugate)

31362-05181 1 x 75 ug, 3 x 30 ug
EUR 702

NUCB2 Antibody, FITC conjugated

1-CSB-PA016146HC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NUCB2. Recognizes NUCB2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Nuclear pore membrane glycoprotein 210 Antibody (HRP)

20-abx108568
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Complement C4-Binding Protein (C4BP) AssayLite Antibody (FITC Conjugate)

11274-05041 150 ug
EUR 513.6

COMMD4 Antibody, FITC conjugated

1-CSB-PA04965C0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against COMMD4. Recognizes COMMD4 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

COMMD1 Antibody, FITC conjugated

1-CSB-PA818712LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against COMMD1. Recognizes COMMD1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

COMMD9 Antibody, FITC conjugated

1-CSB-PA882164LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against COMMD9. Recognizes COMMD9 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

COMMD6 Antibody, FITC conjugated

1-CSB-PA772019LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against COMMD6. Recognizes COMMD6 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

COMMD2 Antibody, FITC conjugated

1-CSB-PA774827LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against COMMD2. Recognizes COMMD2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Pyruvate Dehydrogenase Complex (PDH Complex) AssayLite Antibody (RPE Conjugate)

30022-05151 150 ug
EUR 513.6

Pyruvate Dehydrogenase Complex (PDH Complex) AssayLite Antibody (APC Conjugate)

30022-05161 150 ug
EUR 513.6

COMMD10 Antibody, FITC conjugated

1-CSB-PA809070LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against COMMD10. Recognizes COMMD10 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

POR Antibody, FITC conjugated

1-CSB-PA06275C0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against POR. Recognizes POR from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Human Nuclear Cap-Binding Protein Subunit 2 (NCBP2) Antibody (Biotin Conjugate)

30189-05121 150 ug
EUR 442.8

Pyruvate Dehydrogenase Complex (PDH Complex) AssayLite Multi-Color Conjugated Antibodies Flow Cytometry Kit

FACS30022M Kit
EUR 831.6

Nuclear pore membrane glycoprotein 210 Antibody (Biotin)

20-abx105729
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Capsid protein VP1 Antibody, FITC conjugated

1-CSB-PA362102LC01HPM
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Capsid protein VP1. Recognizes Capsid protein VP1 from Human parvovirus B19. This antibody is FITC conjugated. Tested in the following application: ELISA

Pyruvate Dehydrogenase Complex (PDH Complex) AssayLite Antibody (PerCP Conjugate)

30022-05171 150 ug
EUR 565.2

NUP210 Antibody / Nuclear pore membrane glycoprotein 210

RQ6666 100ug
EUR 356.15
Description: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3.

porB Antibody, FITC conjugated

1-CSB-PA518750LC01NGH
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against porB. Recognizes porB from Neisseria meningitidis serogroup B / serotype 15. This antibody is FITC conjugated. Tested in the following application: ELISA

PORCN Antibody, FITC conjugated

1-CSB-PA887958LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PORCN. Recognizes PORCN from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Cytochrome b-c1 complex subunit Rieske, mitochondrial Polyclonal Conjugated Antibody

C42416 100ul
EUR 476.4

Protein E7 Polyclonal Antibody, FITC Conjugated

A55265
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Protein X Polyclonal Antibody, FITC Conjugated

A50879
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Protein X Polyclonal Antibody, FITC Conjugated

A64288
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Protein P Polyclonal Antibody, FITC Conjugated

A64300
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Nuclear pore membrane glycoprotein 210 Polyclonal Antibody

42276-100ul 100ul
EUR 399.6

Human Complexin-1 (CPX I) AssayLite Antibody (FITC, RPE, APC, PerCP Conjugate)

30025-05181 1 x 75 ug, 3 x 30 ug
EUR 702

Human Nuclear Cap-Binding Protein Subunit 2 (NCBP2) AssayLite Antibody (RPE Conjugate)

30189-05151 150 ug
EUR 513.6

Human Nuclear Cap-Binding Protein Subunit 2 (NCBP2) AssayLite Antibody (APC Conjugate)

30189-05161 150 ug
EUR 513.6

Human Complement C5 AssayLite Antibody (FITC Conjugate)

15051-05041 150 ug
EUR 513.6

Human Complement C6 AssayLite Antibody (FITC Conjugate)

15151-05041 150 ug
EUR 513.6

Human Complement C7 AssayLite Antibody (FITC Conjugate)

15251-05041 150 ug
EUR 513.6

Human Complement C8 AssayLite Antibody (FITC Conjugate)

15351-05041 150 ug
EUR 513.6

Human Complement C9 AssayLite Antibody (FITC Conjugate)

15451-05141 150 ug
EUR 513.6

Human Complement C1 AssayLite Antibody (FITC Conjugate)

12211-05041 150 ug
EUR 513.6

Human Complement C2 AssayLite Antibody (FITC Conjugate)

12221-05041 150 ug
EUR 513.6

Human Complement C3 AssayLite Antibody (FITC Conjugate)

11221-05041 150 ug
EUR 513.6

Human Complement C4 AssayLite Antibody (FITC Conjugate)

11231-05041 150 ug
EUR 513.6

Human Complement C9 AssayLite Antibody (FITC Conjugate)

32034-05141 150 ug
EUR 513.6

Matrix protein Polyclonal Antibody, FITC Conjugated

A54614
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Protein Muc5ac Polyclonal Antibody, FITC Conjugated

A57913
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

PRO1 Antibody, FITC conjugated

1-CSB-PA517332HC01EQB
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PRO1. Recognizes PRO1 from Cynodon dactylon. This antibody is FITC conjugated. Tested in the following application: ELISA

Outer capsid protein VP4 Antibody, FITC conjugated

1-CSB-PA320838LC01ROH
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Outer capsid protein VP4. Recognizes Outer capsid protein VP4 from Rotavirus A. This antibody is FITC conjugated. Tested in the following application: ELISA

Minor capsid protein VP2 Antibody, FITC conjugated

1-CSB-PA355948LC01JAK
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Minor capsid protein VP2. Recognizes Minor capsid protein VP2 from JC polyomavirus. This antibody is FITC conjugated. Tested in the following application: ELISA

Human Complement C1s AssayLite Antibody (FITC Conjugate)

11951-05041 150 ug
EUR 513.6

Human Complement C1q AssayLite Antibody (FITC Conjugate)

11211-05041 150 ug
EUR 513.6

Human Complement C3c AssayLite Antibody (FITC Conjugate)

11222-05041 150 ug
EUR 513.6

Human Complement C4c AssayLite Antibody (FITC Conjugate)

11223-05041 150 ug
EUR 513.6

Human Complement C1r AssayLite Antibody (FITC Conjugate)

11251-05041 150 ug
EUR 513.6

Human Complement C4b AssayLite Antibody (FITC Conjugate)

11254-05041 150 ug
EUR 513.6

Human Complement C3d AssayLite Antibody (FITC Conjugate)

11294-05041 150 ug
EUR 513.6

Human Complement C3b AssayLite Antibody (FITC Conjugate)

11322-05041 150 ug
EUR 513.6

Human Complement C3a AssayLite Antibody (FITC Conjugate)

32554-05141 150 ug
EUR 513.6

Human Complement C4a AssayLite Antibody (FITC Conjugate)

32555-05141 150 ug
EUR 513.6

PROC Antibody, FITC conjugated

1-CSB-PA018742LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PROC. Recognizes PROC from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Human Nuclear Cap-Binding Protein Subunit 2 (NCBP2) AssayLite Antibody (PerCP Conjugate)

30189-05171 150 ug
EUR 565.2

KICSTOR Complex Protein SZT2 (SZT2) Antibody (FITC)

20-abx316295
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Elongator Complex Protein 6 (ELP6) Antibody (FITC)

20-abx317322
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Nuclease P1 Antibody, HRP conjugated

1-CSB-PA328459LB01PEU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Nuclease P1. Recognizes Nuclease P1 from Penicillium citrinum. This antibody is HRP conjugated. Tested in the following application: ELISA

PROCR Antibody, FITC conjugated

1-CSB-PA06329C0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PROCR. Recognizes PROCR from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

PROX1 Antibody, FITC conjugated

1-CSB-PA852905LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PROX1. Recognizes PROX1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Prok2 Antibody, FITC conjugated

1-CSB-PA879446LC01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Prok2. Recognizes Prok2 from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

PRODH Antibody, FITC conjugated

1-CSB-PA018744LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PRODH. Recognizes PRODH from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

mmune subtraction for improved decision in serum protein immunofixation electrophoresis and antibody isotype dedication in a affected person with autoantibody

Heavy chain isotypes of low stage monoclonal immunoglobulins are typically obscured in serum immunofixation electrophoresis (SIFE) by a heavy background of polyclonal immunoglobulins. Nonetheless, correct dedication of the heavy chain isotype is crucial for an entire prognosis, as isotype dedication of autoantibodies could have relevance in figuring out therapeutic procedures. Immune subtraction (IS) was employed in a affected person with neuropathy and GD1a autoantibody. IS allowed identification of the cognate heavy chain associated to a lambda gentle chain restriction famous on preliminary SIFE in addition to isotype dedication of the autoantibody.

Antisera particular to particular person heavy and light-weight chains have been used for depletion of particular immunoglobulin varieties. Depletion of kappa gentle chain related immunoglobulins allowed unequivocal dedication of the isotype of lambda gentle chain-associated low stage monoclonal band to be IgG Lambda. Selective depletion of kappa, lambda, gamma and mu heavy chain immunoglobulins was employed to find out IgG Kappa isotype of the auto-antibody.

Antifreeze Protein Supplementation In the course of the Warming of Vitrified Bovine Ovarian Tissue Can Enhance the Ovarian Tissue High quality After Xenotransplantation

 

The prevalence of ice crystallization throughout ovarian tissue (OT) cryopreservation causes unavoidable cryodamage, and ice recrystallization in the course of the warming is extra detrimental than ice crystallization. Right here, we investigated that antifreeze protein (AFP) therapy in the course of the warming process can enhance the bovine OT high quality after xenotransplantation (XT). Bovine OTs (n=120) have been evenly assigned to 4 teams: recent, vitrified-warmed, vitrified-warmed with 10 mg/mL Leucosporidium ice-binding protein (LeIBP, a kind of AFP) (LeIBP-10), and vitrified-warmed with 20 mg/mL LeIBP (LeiBP-20). LeIBPs have been added to the primary warming resolution. Twenty items of OTs have been assigned to every class. The remaining 10 OTs from every class have been assigned to the XT-Contemporary management, XT-Vitrified-warmed management, XT-LeIBP-10, and XT-LeIBP-20 teams, respectively, and xenotransplanted to 9-week-old ovariectomized nude mice for one week.

LeIBP therapy in the course of the warming step elevated morphological follicle normality and decreased apoptotic follicle ratios after vitrification-warming and XT. The XT-vitrified-warmed management group confirmed considerably decreased microvessel density and elevated fibrosis when in comparison with that of the XT-fresh group. Microvessel density and fibrosis have been recovered in each LeIBP handled teams. There was no important distinction between the LeIBP-10 and LeIBP-20 teams in all outcomes. AFP therapy in the course of the warming process can stop OT injury, and enhance ovarian follicle morphology and apoptosis in each the vitrified-warmed bovine OT and its graft. After affirmation in a human examine, AFPs can doubtlessly be utilized to human OT cryopreservation to scale back cryodamage and enhance the OT high quality.

Doxorubicin/Nucleophosmin Binding Protein-Conjugated Nanoparticle Enhances Anti-leukemia Exercise in Acute Lymphoblastic Leukemia Cells in vitro and in vivo

Acute lymphoblastic leukemia (ALL) is an aggressive malignancy. Adults with ALL have greater than 50% relapse charges. We have now beforehand validated that overexpression of nucleophosmin (NPM) is concerned within the multidrug resistance (MDR) improvement throughout ALL; and a synthetically engineered recombinant NPM binding protein (NPMBP) has been developed in our group; NPMBP and doxorubicin (DOX) might be conjugated in a nanoparticle-based drug supply system named DOX-PMs-NPMBP to counteract MDR throughout ALL. Right here, we evaluated the antileukemia potential of DOX-PMs-NPMBP in resistant ALL cells. This examine demonstrates that DOX-PMs-NPMBP considerably enhances chemosensitivity to DOX in ALL cells.

Regardless of at variable concentrations, each resistant and first ALL cells from relapsed sufferers have been delicate to DOX-PMs-NPMBP. Intimately, the half maximal inhibitory focus (IC50) values of DOX-PMs-NPMBP have been between 1.6- and seven.0-fold decrease than these of DOX in cell strains and first ALL cells, respectively; and apoptotic cells ratio was over 2-fold increased in DOX-PMs-NPMBP than DOX. Mechanistically, p53-driven apoptosis induction and cell cycle arrest performed important function in DOX-PMs-NPMBP-induced anti-leukemia results. Furthermore, DOX-PMs-NPMBP considerably inhibited tumor development and extended mouse survival of ALL xenograft fashions; and no systemic toxicity prevalence was noticed after therapy throughout follow-up. In conclusion, these information point out that DOX-PMs-NPMBP could considerably exert development inhibition and apoptosis induction, and markedly enhance DOX antileukemia exercise in resistant ALL cells. This novel drug supply system could also be invaluable to develop as a brand new therapeutic technique in opposition to multidrug resistant ALL.

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